2023年6月8日，备受血液学领域瞩目的第28届欧洲血液学协会（EHA）年会将如期而至。本次EHA仍然采取线上联合线下综合会议模式。当地时间5月11日18:00，大会摘要公布。小编第一时间检索出21篇中国专家在本届EHA的口头发言，并简要整理，以供大家参考。尽管百密，仍无法确保没有疏漏，欢迎补充。
急性淋巴细胞白血病-临床
摘要号S113： 用CD19嵌合抗原受体T细胞疗法治疗时IKZF1缺失在复发和/或难治性B细胞急性淋巴细胞白血病中的影响
原标题: IMPACT OF IKZF1 DELETION IN RELAPSED AND/OR REFRACTORY B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA TREATED WITH CD19-CHIMERIC ANTIGEN RECEPTOR T-CELL THERAPY
发言人：Zihong Cai
作者: Zihong Cai, Ting Zhang, Suning Chen, Liang Huang, Qifa Liu, Hongsheng Zhou
摘要号S116：捐赠者来源的CD5 CAR-T细胞治疗T细胞急性淋巴细胞白血病
原标题: DONOR-DERIVED CD5 CAR T CELLS FOR T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
发言人：Jing Pan
作者： Jing Pan, Yue Tan, Biping Deng, Zhuojun Ling, Jinlong Xu, Jiajia Duan, Zelin Wang, Kai Wang, Guang Hu
慢性粒细胞白血病-临床
摘要号S158：慢性粒细胞白血病患者在获得主要分子学缓解后使用低剂量酪氨酸激酶抑制剂的疗效
原标题：EFFICACY OF LOW-DOSE TYROSINE KINASE INHIBITOR THERAPY AFTER ACHIEVING MAJOR MOLECULAR RESPONSE IN PERSONS WITH CHRONIC MYELOID LEUKAEMIA
发言人：Qian Jiang
作者: Zongru Li, Yijing Zhao, Linping Lu, Yong Guo, Ya-Zhen Qin, Qian Jiang
侵袭性非霍奇金淋巴瘤-临床
摘要号S234： CD19/BCMA双靶向快速CAR-T GC012F治疗复发/难治性B细胞非霍奇金淋巴瘤患者的首次人体研究的最新临床结果
原标题：UPDATED CLINICAL RESULTS OF FIRST-IN-HUMAN STUDY OF CD19/BCMA DUAL-TARGETING FAST CAR-T GC012F FOR PATIENTS WITH RELAPSED/REFRACTORY B-CELL NON-HODGKIN’S LYMPHOMA
发言人：Yi Zhang
作者: Xinfeng Chen, Yu Ping, Ling Li, Lei Zhang, Xudong Zhang, Jianmin Huang, Jia Liu, Gui Li, Jiaping He, Hua Zhang, Wei Zhao, Lihong Weng, Wenjie Yin, Lianjun Shen, Wei William Cao, Wenling Li, Mingzhi Zhang, Yi Zhang
霍奇金淋巴瘤-临床
摘要号S216：CD47/PD-L1双特异性抗体（IBI322）在抗PD-1或PD-L1治疗的经典霍奇金淋巴瘤中的应用： I期研究
原标题：CD47/PD-L1 BISPECIFIC ANTIBODY (IBI322) IN ANTI-PD-1 OR PD-L1 TREATMENT-RESISTANT CLASSICAL HODGKIN LYMPHOMA: A PHASE I STUDY
发言人：Jingwei Yu
作者: Huilai Zhang, Jingwei Yu, He Li, Wenbin Qian, Xibin Xiao, Qingqing Cai, Yao Liu, Yu Zhang, Liling Zhang, Ling Qin, Hui Zhou, Xiaoyi Tang, Yingmei Guo, Ting Niu
骨髓增生性肿瘤-生物学与转化研究
摘要号S207：Navtemadlin，一种口服的MDM2抑制剂，在MPN-BP PDX模型中显示可消除MPN-BP期启动细胞并延长无白血病生存期（LFS）
原标题：NAVTEMADLIN, AN ORAL MDM2 INHIBITOR, ELIMINATES MYELOPROLIFERATIVE NEOPLASM-BLAST PHASE (MPN-BP) INITIATING CELLS AND PROLONGS LEUKEMIA-FREE SURVIVAL (LFS) IN AN MPN-BP PDX MODEL
发言人：Xiaoli Wang
作者: Xiaoli Wang, Cing Siang Hu, Andrew Davis, Cecile Krejsa, Ronald Hoffman
骨髓增生性肿瘤-临床
摘要号S212：Jaktinib vs 羟基脲治疗中危-2或高危风险骨髓纤维化患者的随机双盲3期研究
原标题：A RANDOMIZED DOUBLE-BLIND PHASE 3 STUDY OF JAKTINIB VERSUS HYDROXYUREA IN PATIENTS WITH INTERMEDIATE-2 OR HIGH RISK MYELOFIBROSIS
发言人：Yi Zhang
作者: Yi Zhang, Hu Zhou, Junling Zhuang, Aili He, Yarong Li, Linhua Yang, Xin Du, Sujun Gao, Guangsheng He, Mei Hong, Qian Jiang, Zhongxing Jiang, Sun Kai, Lingling Yue, Cuiping Zheng, Zeping Zhou, Chenghao Jin, Hongmei Jing, Lin Liu, Qingchi Liu, Jishi Wang, Wen Wu, Yajing Xu, Dengshu Wu, Na Xu, Feng Zhang, Jin Zhang, Huanling Zhu, Zhijian Xiao, Jie Jin
血液学感染 (包括治疗和支持治疗)
摘要号S291：CMV/EBV特异性T细胞用于单倍体干细胞移植后CMV和EBV共同再活化的长期安全性和有效性
原标题：LONG-TERM SAFETY AND EFFICACY OF CMV/EBV-SPECIFIC T CELLS FOR CMV AND EBV CO-REACTIVATION AFTER HAPLOIDENTICAL STEM CELL TRANSPLANTATION
发言人：Pei Xuying
作者: Pei Xuying, Xiangyu Zhao, Meng Lv, Jing Liu, Lanping Xu, Yu Wang, Xiao-Hui Zhang, Xiao-Jun Huang
摘要号S293：双元基因组学二代测序的新方法用于发热性中性粒细胞减少症血液病患者血流感染的早期诊断：一项多中心、前瞻性研究
原标题：A NOVEL APPROACH OF DUAL METAGENOMICS NEXT-GENERATION SEQUENCING FOR EARLY DIAGNOSIS OF BLOOD STREAM INFECTION IN HEMATOLOGIC PATIENTS WITH FEBRILE NEUTROPENIA: A MULTICENTER, PROSPECTIVE STUDY
发言人：Yuqian Sun
作者: Yuqian Sun, Jing-Rui Zhou, Yue Yin, Jian-Ping Zhang, meixiang zhang, Yun He, Xiaojun Huang
干细胞移植-临床
摘要号S246：JAK/ROCK抑制剂TQ05105治疗糖皮质激素难治性或依赖性慢性移植物抗宿主病：1B/2期研究的最新结果
原标题：JAK/ROCK INHIBITOR TQ05105 FOR GLUCOCORTICOID-REFRACTORY OR -DEPENDENT CHRONIC GRAFT-VERSUS-HOST DISEASE：UPDATED RESULTS OF A PHASE 1B/2 STUDY
发言人：He Huang
作者: Yanmin Zhao, Lifan Tu, Yi Luo, Jimin Shi, Yishan Ye, Jian Yu, Yi Yu, Shunqing Wang, Fankai Meng, Erlie Jiang, Xiaoyu zhu, Yang Yu, He Huang
摘要号S247：在BU/CY预处理方案中加入ruxolitinib和decitabine以预防高危AML移植后复发是安全和有效的：一项前瞻性II期研究
原标题：ADDING RUXOLITINIB AND DECITABINE TO BU/CY CONDITIONING REGIMENS TO PROPHYLAXIS POST-TRANSPLANT RELAPSE IN HIGH-RISK AML IS SAFE AND EFFECTIVE: A PROSPECTIVE, PHASE Ⅱ STUDY
发言人：Dai-Hong Liu
作者: Yujun Wei, Kun Qian, Lili Wang, Fei Li, Nan Wang, Bo Peng, Yanan Wen, Lu Wang, Lingmin Xu, Xiangshu Jin, Liping Dou, Dai-Hong Liu
摘要号S290：异基因造血干细胞移植后成人患者闭塞性支气管炎综合征预后模型的开发和验证
原标题：DEVELOPMENT AND VALIDATION OF A PROGNOSTIC MODEL OF BRONCHIOLITIS OBLITERANS SYNDROME IN ADULT PATIENTS FOLLOWING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION
发言人：Qiu-Sha Huang
作者: Qiu-Sha Huang, Tian-Xiao Han, Xiao-Lu Zhu, Hai-Xia Fu, Yun He, Feng-Rong Wang, Yuan-Yuan Zhang, Xiao-Dong Mo, Wei Han, Jing-Zhi Wang, Yu Wang, Huan Chen, Yu-Hong Chen, Chen-Hua Yan, Yuan Kong, Xiang-Yu Zhao, Ying-Jun Chang, Lan-Ping Xu, Kai-Yan Liu, Xiao-Jun Huang, Xiao-Hui Zhang
干细胞移植-实验室
摘要号S240：通过减少T和B的恶性遗传，靶向PRMT1可减轻慢性移植物抗宿主病的影响
原标题：TARGETING PRMT1 ALLEVIATES CHRONIC GRAFT-VERSUS-HOST DISEASE BY REDUCING T AND B PATHOGENICITY
发言人：Xiaoyan Zhao
作者: Xiaoyan Zhao, Li Cai, Huafang Wang
摘要号S241：ITACONATE通过NRF2抑制Th1分化和急性移植物抗宿主疾病
原标题：ITACONATE INHIBITS TH1 DIFFERENTIATION AND ACUTE GRAFT-VERSUS-HOST DISEASE VIA NRF2
发言人：Yaoyao Shen
作者: Huanle Gong, Yaoyao Shen, Yang Xu, Depei Wu
摘要号S243：AGVHD期间T细胞产生的乳酸通过组蛋白修饰促进T细胞激活的第二信号生成
原标题：LACTATE PRODUCED BY T CELLS DURING AGVHD PROMOTES SECOND SIGNAL GENERATION FOR T CELL ACTIVATION THROUGH HISTONE MODIFICATION
发言人：Hengwei Wu
作者: Hengwei Wu, Xin Jin, Fei Gao, He Huang, Yanmin Zhao
地中海贫血
摘要号S271：BRL-101的最新更新：CRISPR-CAS9介导的BCL11A的基因编辑延长输血依赖性β-地中海型贫血的治疗
原标题：AN UPDATED FOLLOW-UP OF BRL-101, CRISPR-CAS9-MEDIATED GENE EDITING OF THE BCL11A ENHANCER FOR TRANSFUSION-DEPENDENT BETA-THALASSE
发言人：Biao Zheng
作者: Bin Fu, Xinhua Zhang, Li Wang, Jiaoyang Liao, Shuanghong Chen, Biao Zheng, Wei Li, Fei Wang, Dali Li, Mingyao Liu, Yuxuan Wu
摘要号S272：RM-001对输血依赖性β-地中海贫血患者的安全性和有效性：来自自体HBG1/2启动子修饰的CD34+造血干细胞和祖细胞的早期结果
原标题：SAFETY AND EFFICACY OF RM-001 IN PATIENTS WITH TRANSFUSION-DEPENDENT Β-THALASSEMIA: EARLY RESULTS FROM THE ONGOING OF AUTOLOGOUS HBG1/2 PROMOTER-MODIFIED CD34+ HEMATOPOIETIC STEM AND PROGENITOR CELLS
发言人：Rongrong Liu
作者: Rongrong Liu, Li Wang, Hui Xu, Xiaolin Yin, Junbin Liang, Wenqiang Xie, Gaohui Yang, Yaoyun Li, Yali Zhou, Lei Shi, Bin Xiao, Lingling Shi, Zeyan Shi, Xuemei Zhou, Jianpei Fang, Xiangmin Xu, Yongrong Lai, Junjiu Huang, Xinhua Zhang
酶病、膜病和其他贫血
摘要号S275：PUS1通过TRNA假酸化和细胞质翻译调控红细胞生成
原标题：PUS1 REGULATES ERYTHROPOIESIS VIA TRNA PSEUDOURIDYLATION AND CYTOPLASMIC TRANSLATION
发言人：Yajing Chu
作者: Yajing Chu, Deyang Shi, Bichen Wang, Yu Lian, Haoyuan Li, Qiuyi Ma, Tong Liu, Mutian Cao, Jun Shi, Weiping Yuan
出血性疾病(先天性和获得性)
摘要号S299：Orelabrutinib，一种不可逆的布鲁顿酪氨酸激酶抑制剂，用于治疗原发性免疫性血小板减少症：一项随机、开放标签、2期研究结果
原标题：ORELABRUTINIB, AN IRREVERSIBLE INHIBITOR OF BRUTON’S TYROSINE KINASE, FOR TREATMENT OF PRIMARY IMMUNE THROMBOCYTOPENIA: RESULTS OF A RANDOMIZED, OPEN-LABEL PHASE II STUDY
发言人：Ming Hou
作者: Yan Shi, Hu Zhou, Ruibin Huang, Fang Wang, Heng Mei, Lie Lin, Jingming Guo, Xin Zhou, Zhenyu Li, Yaorong Liu, Sichen Li, Wei Zhou, Ming Hou
血小板疾病
摘要号S295：TACROLIMUS通过MTHFD2调节免疫性血小板减少症中CD4+T细胞的增殖和功能
原标题：TACROLIMUS MODULATES CD4+ T-CELL PROLIFERATION AND FUNCTION VIA MTHFD2 IN IMMUNE THROMBOCYTOPENIA
发言人：Li-Ping Yang
作者: Li-Ping Yang, Hai-Xia Fu, Qiu-sha Huang, Peng Zhao, Chen-Cong Wang, Yuan-Yuan Zhang, Xiao-Jun Huang, Xiao-Hui Zhang
摘要号S296：IL-1Β信号诱导及BARICITINIB缓解免疫性血小板减少症中NEU1介导的巨核细胞脱亚甲基化现象
原标题：IL-1Β SIGNALLING INDUCES, AND BARICITINIB ALLEVIATES NEU1-MEDIATED MEGAKARYOCYTE DESIALYLATION IN IMMUNE THROMBOCYTOPENIA
发言人：Peng Zhao
作者: Peng Zhao, Zhuo-yu An, Hai-xia Fu, Hui-xin Liu, Li-ping Yang, Qing-yuan Qu, Qiu-sha Huang, Jin Wu, Ye-jun Wu, Yu-xiu Chen, Meng-lin Li, Chencong Wang, Xiaolu Zhu, Yun He, Juan-juan Li, Yuan-yuan Zhang, Qian Jiang, Hao Jiang, Jin Lu, Ying-jun Chang, Xiao-su Zhao, Xiang-yu Zhao, Xiao-jun Huang, Xiao-Hui Zhang
以上oral均为中国研究者领衔开展的研究，筛选自于EHA官网，若有遗漏，欢迎留言补充。谢谢！
https://ehaweb.org/congress/eha2023-hybrid-congress/eha2023/
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