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【2023 ESMO】新药研发领域口头摘要信息速览!

2023年08月22日
编译:肿瘤资讯
来源:肿瘤资讯

2023年ESMO大会将于10月20日-24日在西班牙马德里举行,大会涵盖了肿瘤领域的基础研究、转化研究以及最新的临床研究进展,为临床实践、多学科讨论等提供广阔、卓越的学术平台。


近日,ESMO官方已公布除Late-breaking abstracts(LBA)外的所有口头摘要题目及作者信息。【肿瘤资讯】特别整理本次公布的新药研发领域重磅研究(主要包含MO:mini oral;O:oral)标题,以飨读者。


Mini oral session

本专场有3个LBA摘要待确认(TBC)

专场时间:2023年10月23日,16:30-18:00

专场地点:Valencia Auditorium - Hall 10


摘要号:656MO

靶向HER2 ADC SHR-A1811治疗HER2表达/突变的晚期非乳腺实体瘤:全球1期研究结果

The HER2-targeting ADC SHR-A1811 in HER2-expressing/mutated advanced non-breast solid tumors (STs): results from the global phase 1 study

讲者:姚和瑞(中国广州)


摘要号:657MO

抗体免疫刺激偶联药物(ISAC)BDC-1001在晚期表达HER2实体瘤患者(pts)中的首次人体推荐2期剂量(RP2D)选择和药效学(PD)数据

Recommended phase 2 dose (RP2D) selection and pharmacodynamic (PD) data of the first-in-human immune-stimulating antibody conjugate (ISAC) BDC-1001 in patients (pts) with advanced HER2-expressing solid tumors

讲者:Bob T. Li (New York, United States of America)

 

摘要号:658MO

靶向HER3 ADC SHR-A2009在晚期实体瘤中的1期研究

Phase 1 study of SHR-A2009, a HER3-targeted ADC, in advanced solid tumors

讲者:周清(中国湛江)


摘要号:659MO

9MW2821(一种靶向Nectin-4的抗体药物偶联物)在晚期实体瘤患者中的I/II期研究的初步结果

Preliminary results from a phase I/II study of 9MW2821, an antibody-drug conjugate targeting Nectin-4, in patients with advanced solid tumors

讲者:张剑(中国上海)


摘要号:660MO

靶向B7-H4 ADC SGN-B7H4V在晚期实体瘤患者中的首次人体研究:1期研究的初步结果(SGNB7H4V-001)

First-in-human study of SGN-B7H4V, a B7-H4-directed vedotin ADC, in patients with advanced solid tumors: Preliminary results of a phase 1 study (SGNB7H4V-001)

讲者:Cesar A. Perez (Fort Myers, United States of America)


摘要号:661MO

Belvarafenib联合Cobimetinib对携带BRAF融合或BRAF II/III类突变的转移性实体瘤患者的抗肿瘤活性

Anti-Tumor Activity of Belvarafenib in combination with Cobimetinib in patients with metastatic solid tumors harboring BRAF fusions or BRAF class II/III mutation

讲者:Tae Won Kim (Seoul, Korea, Republic of)


摘要号:662MO

WEE1抑制剂IMP7068在晚期实体瘤患者中的1期多中心剂量递增和剂量扩展研究

Phase 1, Multi-Center, Dose-escalation and Dose-expansion Study of IMP7068, a WEE1 Inhibitor, in Patients with Advanced Solid Tumors

讲者:Chia-Chi Lin (Taipei City, Taiwan)


Proffered Paper session

本专场有1个LBA摘要待确认(TBC)

专场时间:2023年10月22日

专场地点:Málaga Auditorium - Hall 10

专场主席:Lillian L. Siu (Toronto, Canada) Elena Garralda (Barcelona, Spain)


摘要号:652O

RMC-6236(一种新型RAS-选择性、三复合RAS-MULTI(ON)抑制剂)在KRAS突变型胰腺导管腺癌(PDAC)和非小细胞肺癌(NSCLC)患者中的初步临床活性

Preliminary clinical activity of RMC-6236, a first-in-class, RAS-selective, tri-complex RAS-MULTI(ON) inhibitor in patients with KRAS mutant pancreatic ductal adenocarcinoma (PDAC) and non-small cell lung cancer (NSCLC)

讲者:Kathryn C. Arbour (New York, United States of America)


摘要号:653O

Glecirasib(KRAS G12C抑制剂)与JAB-3312(SHP2抑制剂)联合治疗KRAS p.G12C突变实体瘤患者

Glecirasib (KRAS G12C inhibitor) in combination with JAB-3312 (SHP2 inhibitor) in Patients with KRAS p.G12C mutated solid tumors.

讲者:王洁 (中国北京)


摘要号:654O

曲妥珠单抗(T-DXd)治疗HER2阳性实体瘤患者(pts)的疗效和安全性:国际2期DESTINY-PanTumor01(DPT-01)研究的主要结果

Efficacy and safety of trastuzumab deruxtecan (T-DXd) in patients (pts) with solid tumors harboring specific HER2-activating mutations (HER2m): primary results from the international phase 2 DESTINY-PanTumor01 (DPT-01) study

讲者:Bob T. Li (New York, United States of America)


摘要号:655O

Cofetuzumab Pelidotin(一种抗-PTK7抗体药物偶联物)在表达PTK7复发性非小细胞肺癌(rNSCLC)患者中的1b期研究

Phase 1b Study of Cofetuzumab Pelidotin, an Anti-PTK7 Antibody-Drug Conjugate, in Patients with PTK7-Expressing Recurrent Non-Small Cell Lung Cancer (rNSCLC)

讲者:Byoung Chul Cho (Seoul, Korea, Republic of)


责任编辑:肿瘤资讯-云初
排版编辑:肿瘤资讯-云初



               
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