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SABCS 2023壁报展|中国150余项研究入选壁报——POSTER session 2

2023年11月16日
整理:肿瘤资讯
来源:SABCS官网

2023年第46届圣安东尼奥乳腺癌研讨会(San Antonio Breast Cancer Symposium,SABCS)将于12月5日至9日在美国得克萨斯州圣安东尼奥举行。该会议汇聚了全球约1万名临床医生和专家,是规模最大、最具影响力的乳腺癌研究盛会。

日前,大会公布了本次会议的详细日程及研究题目,150余项中国研究成果入选SABCS POSTER session。【肿瘤资讯】从官网获得现有资讯,将入选POSTER session 2的中国研究信息整理如下,以飨读者。

PO2-01-04 Efficacy and safety of anti-HER2 therapy in neoadjuvant therapy for HER2-positive breast cancer: a network meta-analysis. 

作者:Lu Gan,Fangxuan Li,Jialin Su

第一作者单位:The First Affiliated Hospital of Chongqing Medical University

PO2-01-05 Neoadjuvant pyrotinib plus trastuzumab, and chemoterapy in patients with HER2-positive early breast cancer: a real-world study. 

作者:Jun Zhou,Rui Wang

第一作者单位:Department of Breast Cancer,   The first people's hospital of lianyungang

PO2-02-05 CDK4/6 inhibitor dalpiciclib combined with letrozole as neoadjuvant therapy in  postmenopausal patients with hormone receptor-positive, HER2-negative stage II-III breast cancer: a single-arm exploratory   trial.

作者:Lina Zhang,Chao Yang,Jie Ma,Yuntao Li,Ruizhen   Luo,Jianjun Han,Xiaochun Wang,Zhisheng Zhang,Li Ma,Haifeng Cai,Xiangshun Kong,Zunyi Wang,Xinping Zhou,Yueping Liu,JiaJie Shi,Yanshou Zhang,Meiqi Wang,Jiaxing Wang,Cuizhi Geng

第一作者单位:Breast Center, The Fourth Hospital of Hebei Medical University

PO2-02-07 Clinicopathological Features and Prognostic Role of HER2 Low in Early Breast Cancer: A real  world study.

作者:Ziqing Kong,Weihong Zhao

第一作者单位:Department of Medical Oncology, the First Medical Center, Chinese PLA General Hospital

PO2-03-05 Neoadjuvant anthracycline followed by Toripalimab combined with nab-paclitaxel in  patients with stage IIA-IIIC triple negative breast cancer (NeoTENNIS): efficacy and safety   results of a  phase II study. 

作者:Min He,Linxiaoxi Ma,Shuang Hao,Benlong Yang,Bingqiu Xiu,Ya-Yun Chi ,Ruo-Hong Shui,Zhong-Hua Wang,Zhi-Ming Shao,Jiong Wu

第一作者单位:Fudan University Shanghai   Cancer Center

PO2-03-11 A novel peripheral CD4+ T cell immune network associated with response to PD-1 inhibitor in early-stage triple negative breast cancer. 

作者:Zehao Wang,Zhibo Shao,Bingqiu Xiu,Jiong Wu 

第一作者单位:Fudan University Shanghai   Cancer Center

PO2-04-02 Trends in Disparities and Transitions of target therapy in Patients With ERBB2 Positive Early Breast Cancer in China and the US, 2011 to 2021.

作者:Jianbin Li,Jifang Zhou,Haibo Wang,Zhenzhen liu,Zhimin Fan,Yinhua Liu,Cuizhi Geng,Zefei Jiang

第一作者单位:China Pharmaceutical University

PO2-04-03 BL-M07D1, an antibody-drug conjugate directed to HER2  in patients with locally advanced  or metastatic  Breast Cancer with HER2-positive/low-expression  and other solid tumors: Results from  a first-in-human phase 1 study. 

作者:Erwei Song,Herui Yao,Meili Sun,Hong Zong,Rongbo Lin,Wen Zou,Muran Ding,Jing Yu,Sa Xiao,Hongwei Wang,Hai Zhu,Martin Olivo,Yi Zhu

第一作者单位:Breast Tumour Centre, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China

PO2-04-07 Efficacy and Safety of First-line Therapy in Patients with HER-2 positive Advanced Breast  Cancer:A network Meta-analysis of Randomized Controlled Trials. 

作者:junxiao wang,Yushuai Yu,Jie Zhang,Chuangui Song

第一作者单位:The Second Hospital of Sanming, China (People's Republic)

PO2-05-01 Famitinib, a multi-targeted receptor tyrosine kinase   inhibitor, combined with dalpicilib and fulvestrant in advanced HR-positive and HER2-negative breast cancer. 

作者:Min Yan,Mengwei Zhang,Limin Niu,Huimin Lv,Zhenzhen Liu,Huiai zeng,Shengnan Zhao,Huihui Sun,Jing  Wang,Yajing Feng,Huajun Li

第一作者单位:Henan Cancer Hospital


PO2-05-12 Retrospective analysis on therapeutic efficacy and predictive indicators of eribulin plus anti-angiogenic drugs for metastatic breast cancer. 

作者:Junmei Zhang,Xuezheng Wang,hongjuan Du ,Yan Xue

第一作者单位:Department of Medical Oncology, XI’AN International medical center hospital

PO2-05-13 HER2 status presented an unstable switching from primary to recurrent breast cancer.  

作者:Anjie Zhu,Hui-Ping Li

第一作者单位:Key Laboratory of Carcinogenesis and Translational Research (Ministry of   Education/Beijing),  Department of   Breast Oncology, Peking University    Cancer Hospital & Institute

PO2-06-09 A prospective phase 2 study on efficacy and safety of AK105, anlotinib combined with nab- paclitaxel (nab-P) as a first-line therapy in patients(pts) with advanced triple-negative breast  cancer (TNBC).

作者:Liang Zhang,Tao Sun

第一作者单位:Department of Medical Oncology, Cancer Hospital of China Medical University, Liaoning   Cancer  Hospital and & Institute,   Key Laboratory of Liaoning Breast Cancer Research

PO2-06-11 A phase II randomized trial of gemcitabine plus cisplatin(GP) vs gemcitabine plus carboplatin (GC) as the first-line treatment for patients with metastatic triple-negative   breast cancer. 

作者:Chengcheng Gong,Yannan Zhao,Leiping Wang,jun Cao,Zhonghua Tao,Ting Li,Mingchuan Zhao,Haitao Miao,Juan Jin,Xichun Hu,Biyun Wang

第一作者单位:Fudan University Shanghai Cancer Center

PO2-06-14 Kynurenine induces senescence reprogramming to promote metastasis in young triple- negative breast cancer. 

作者:Cui-Cui Liu,Ke-da Yu

第一作者单位:Cancer Center and Cancer Institute, Shanghai Medical College, Fudan University

PO2-08-02 Evaluation of predictive and prognostic value of androgen receptor expression in breast cancer subtypes treated with neoadjuvant   chemotherapy. 

作者:Jin Zhang 

第一作者单位:The 3rd Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin,  Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and   Therapy,  Tianjin Medical University, Ministry of Education  

PO2-13-04 Single cell characterization of senescent CD8+ T cell promotes   immunotherapy resistance in early-stage triple-negative breast cancer. 

作者:Tong Fu,Yi-Yu Chen,Xi Jin,Yi-Zhou Jiang,Zhi- Ming Shao

第一作者单位:Fudan University Shanghai Cancer Center

PO2-15-02 Personalized circulating tumor DNA (ctDNA) monitoring can early identify disease  progression and predict prognosis in patients with breast cancer undergoing neoadjuvant   therapy. 

作者:Yunjiang Liu,Chao Shi,Xiangmei Zhang,Xiaofei Ren,Shang Wu,Yaxian Wang,Yue  Che,Zanmei Xu,Fei Pang

第一作者单位:Department of Breast Center,   Fourth Hospital of Hebei Medical University

PO2-16-06 Treatment Patterns of Neoadjuvant Therapy in Chinese Patients with HR-Positive/HER2- Positive Early or Locally Advanced Breast Cancer: A Real-World Study Using NCID Data in 2019-2022.

作者:Zhenzhen Liu,Jiujun Zhu,Chengzheng Wang,Zhenduo Lu,Xiuchun Chen,Lianfang Li ,Xianfu Sun,Chongjian Zhang,Jianghua Qiao ,Min Yan 

第一作者单位:Department of Breast Disease, Henan Breast Cancer Center. The Affiliated Cancer Hospital of  Zhengzhou University & Henan Cancer Hospital

PO2-16-08 Adjuvant Treatment Selection for County-Level Patients with HR+/HER2- Early Breast  Cancer in a Real-Life Setting in China. 

作者:Yinghua Ji,Honglan Qu,Feidu Zhou,Juan Wang,Qianfu Wu,Guohua Dai,Mengyou Liu,Wenbo He,Wei Liang,Qiuli Meng,Yun Ren ,Guoxiang Luo,Hongjian Wang,Hui Liu,Zien Qin,Yingguo   Tian,Huali Tang ,Hongmei Liu,Jun Luo,Zengfeng Yu   Guinv Hu   Jianzhi Gao   Xiang Tan   Yi    Liu   Yuanjiang Zhang     Ming Wang   Min Zhang,Ping Lu     

第一作者单位:The First Affiliated Hospital of Xinxiang Medical University

PO2-17-03 Patient reported outcomes (PROs) and survival with toremifene versus aromatase  inhibitors (AI) in   patients with moderate/high-risk premenopausal hormone receptor (HR)-positive  breast cancer: A real-world study. 

作者:Yaping   Yang,Fengxia Gan,Wenqian Yang,Yuan Xia,Qiang Liu,Chang Gong

第一作者单位:Sun Yat-Sen Memorial Hospital   of Sun Yat-Sen University

PO2-17-04 Landscape of young breast cancer under 35 years in China over the past decades: a  multicentre retrospective cohort study (YBCC-Catts study). 

作者:xue Wang,changfa xia,yu wang,yixin qi,Xiaowei Qi,Jiuda zhao,songqing ye,zixuan lei,Jian Yue,hairong huang,ning liu,wanqing chen,peng yuan,Binghe Xu

第一作者单位:National Cancer Center/Cancer   Hospital, Chinese Academy of Medical   Sciences & Peking Union  Medical College

PO2-18-12 Updated Results of a Phase II Study: Neoadjuvant Inetetamab Combined with Pertuzumab, Paclitaxel and Carboplatin for Locally Advanced HER2-Positive Breast Cancer. 

作者:Yue Chai,Jiaxuan Liu ,Mingxia Jiang,Maiyue He,Xin Wang,Yipeng Wang,Xue Yang,Jing Wang,Binghe  Xu,Qiao Li

第一作者单位:Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

PO2-23-08 High intratumor heterogeneity induced PSME2 confers endocrine resistance via ERα PARylation in hormone receptor-positive and   HER2-negative breast cancer. 

作者:Li-Ping Ge,Zi-Yu Wang ,Xi Jin,Yi-Zhou Jiang,Zhi-Ming Shao

第一作者单位:Fudan University Shanghai   Cancer Center

PO2-23-11 SMAD4 depletion contributes to endocrine therapy resistance by ERBB signaling in  HR+HER2- breast cancer.

作者:Kang Li,Dan Shu,Han Li

第一作者单位:The First Affiliated Hospital of   Chongqing Medical University

PO2-24-12 Tumor-specific circRNAs elicit anti-tumor immune response via encoding cryptic antigenic  peptides.   

作者:Di Huang,Jianing Chen,Shicheng Su,Erwei Song

第一作者单位:Sun Yat Sen Memorial Hospital 

PO2-25-02 The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple- negative breast cancer.

作者:Hai Wang

作者单位:Fudan University Shanghai Cancer Center 

PO2-25-04 Anti-TIGIT upregulate CD226 on CD8+T cell as a potential therapeutic manner in HER2  positive   breast cancer. 

作者:Liyi Zhang,Qi Zhang,Zehao Wang,Zhibo Shao,Jingyan Xue,Yayun Chi,Bingqiu Xiu,Jiong Wu

第一作者单位:Department of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Fudan University Shanghai Cancer Center, Shanghai, China. Department of Oncology, Fudan University Shanghai Medical  College

PO2-27-01 TFX06, a next-generation oral CERAN/SERD, shows favorable safety and PK profile,  extracranial and intracranial efficacy in patients with ER+/HER2- breast cancer:   Preliminary results  from a phase 1/2 first-in-human trial. 

作者:Zhaojian Fu,Zhiye Zhang,Jia Song,Yang Chen,Douglas Fang,Wei Sha,Jian Zhang,Charles Ding

第一作者单位:VyBio

PO2-27-11 Antitumor efficacy and safety of sacibertinib (Hemay022) in combination with endocrine  therapy in patients with ER+ and HER2+ metastatic breast cancer: A phase Ib study.   

作者:Hui-Ping Li,Qingyuan Zhang,Ruyan Zhang,Yaxin Liu,Chang Liu,Xianjun Hu

第一作者单位:Department of Medical Oncology, Peking University Cancer Hospital & Institute


SABCS中国之声总览:

Rapid Fire Session: Mini-Oral Presentations、POSTER SPOTLIGHT Session

POSTER Session 1

POSTER Session 3

POSTER Session 4

POSTER Session 5

本文检索了POSTER SESSIONS中第一作者单位为中国单位的研究。如果有任何错误或遗漏,请联系我们进行修改。

资料来源

http://www.sabcs.org/FullProgram

责任编辑:肿瘤资讯-Paine
排版编辑:肿瘤资讯-张薪媛


               
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