2025年3月26日~30日,第34届亚太肝脏研究协会年会(APASL 2025)将在中国北京隆重举行。本次大会以“多学科协作:消除与治愈”为主题,旨在全面展示全球肝病研究领域的最新成果与前沿趋势。目前,大会摘要标题已公布,【肿瘤资讯】特整理肝胆胰肿瘤领域的中国Later Breaker和Oral研究,与读者一同领略中国之声。
Later Breaker
摘要号:LB0003
英文标题:Durvalumab and Tremelimumab as First-line Treatment in Patients with Unresectable Hepatocellular Carcinoma: Interim Analysis of An Open-label, Multi-center Phase IIIb Study (TREMENDOUS study)
中文标题:度伐利尤单抗和替西木单抗作为不可切除肝细胞癌一线治疗:一项开放标签、多中心IIIb期研究的中期分析(TREMENDOUS研究)
汇报人:樊嘉
时间:3月29日08:00-08:48
Oral
摘要号:AA0004
英文标题:Tertiary lymphoid structures in hepatocellular carcinoma: influence on immune cell profiles in tumors and on efficacy of adjuvant PD-1 inhibitor therapy after hepatectomy
中文标题:肝细胞癌中的三级淋巴结构:对肿瘤免疫细胞谱和肝切除术后辅助PD-1抑制剂治疗疗效的影响
汇报人:JiaYong Su
时间:3月26日13:35-15:05
摘要号:AA0019
英文标题:Distinct molecular pathways regulated by activated AKT and YAP signaling during intrahepatic cholangiocarcinoma progression
中文标题:肝内胆管癌进展过程中受激活的AKT和YAP信号传导调节的不同分子通路
汇报人:Jinqiu Zhao
时间:3月26日13:35-15:05
摘要号:AA0021
英文标题:Single-cell Spatial Proteomic Landscape of Intrahepatic Cholangiocarcinoma Immune Microenvironment Reveals Immune Evasion via FSTL1-negative Macrophage
中文标题:肝内胆管癌免疫微环境的单细胞空间蛋白质组学景观揭示了通过FSTL1阴性巨噬细胞的免疫逃逸
汇报人:Wenzhu Li
时间:3月26日13:35-15:05
摘要号:AA0029
英文标题:HBV replication facilitates drug resistance of hepatocellular carcinoma via CD133 regulating self-renewal of liver cancer stem cells
中文标题:HBV复制通过CD133调节肝癌干细胞的自我更新促进肝细胞癌的耐药性
汇报人:Kuanhui Xiang
时间:3月26日13:35-15:05
摘要号:AA0044
英文标题:Disease time burden in patients with advanced hepatocellular carcinoma receiving systemic therapy
中文标题:接受全身治疗的晚期肝细胞癌患者的病程负担
汇报人:Matthew ShingHin Chung
时间:3月26日13:35-15:05
摘要号:OP0009
英文标题:Targeted Therapy with GPC3-Loaded Exosomes: IR780-Based Thermotherapy and Lenvatinib Chemotherapy in Hepatocellular Carcinoma
中文标题:负载GPC3的外泌体靶向治疗:基于IR780的热疗和仑伐替尼化疗治疗肝细胞癌
汇报人:Shenan Huang
时间:3月28日13:15-14:15
摘要号:OP0010
英文标题:CXCL2 Potentiates Neutrophil-mediated Anti-tumor Immunity by Inhibiting Cholesterol Biosynthesis in Hepatocellular Carcinoma
中文标题:CXCL2通过抑制肝细胞癌中胆固醇的生物合成增强中性粒细胞介导的抗肿瘤免疫
汇报人:Xin Liu
时间:3月28日13:15-14:15
摘要号:OP0011
英文标题:A Multi-institutional Analysis of Risk Factors and Predictive Model for Distant Metastasis After Hepatic Resection for Hepatocellular Carcinoma
中文标题:肝细胞癌肝切除术后远处转移的危险因素及预测模型的多机构分析
汇报人:Tian Yang
时间:3月28日13:15-14:15
摘要号:OP0038
英文标题:CHEK1 suppresses hepatocellular carcinoma progression by modulating reprogramming of tumor-associated macrophages
中文标题:CHEK1通过调节肿瘤相关巨噬细胞的重编程来抑制肝细胞癌进展
汇报人:Yanqiu Li
时间:3月28日14:15-15:15
摘要号:OP0041
英文标题:Pathological Study of the Tumor Microenvironment After Neoadjuvant Therapy in Hepatocellular Carcinoma: Why Does TACE Combined with Anti-Angiogenics and Immunotherapy Outperform TACE Alone?
中文标题:肝细胞癌新辅助治疗后肿瘤微环境的病理研究:为什么 TACE 联合抗血管生成和免疫治疗优于单独使用 TACE?
汇报人:Xintao He
时间:3月28日14:15-15:15
摘要号:OP0042
英文标题:Classifications and Outcomes of Local Tumor Progression of Hepatocellular Carcinoma after Thermal Ablation: A Longitudinal Multicenter Study
中文标题:热消融术后肝细胞癌局部肿瘤进展的分类和结果:一项纵向多中心研究
汇报人:Fangying Fan
时间:3月28日14:15-15:15
摘要号:OP0068
英文标题:Efficacy and Safety of Immune Checkpoint Inhibitor Rechallenge in Unresectable Hepatocellular Carcinoma: A Retrospective, Multicenter Cohort Study
中文标题:免疫检查点抑制剂再挑战治疗不可切除肝细胞癌的疗效和安全性:一项回顾性、多中心队列研究
汇报人:JingKun Chen
时间:3月28日15:30-16:30
摘要号:OP0069
英文标题:The Impact and Mechanisms of Neurofibromin 1 (NF1) on the Progression of Intrahepatic Cholangiocarcinoma
中文标题:神经纤维瘤蛋白1(NF1)对肝内胆管癌进展的影响和机制
汇报人:Zhengfeng Xuan
时间:3月28日15:30-16:30
摘要号:OP0070
英文标题:Impact of Immune-Related Adverse Events on Survival in the Immunotherapy of Advanced Hepatocellular Carcinoma
中文标题:免疫相关不良事件对晚期肝细胞癌免疫治疗生存率的影响
汇报人:Nan Zhang
时间:3月28日15:30-16:30
摘要号:OP0071
英文标题:Efficacy and safety of pembrolizumab and lenvatinib in combination with GEMOX via different administration routes (HAIC vs intravenous) in advanced intrahepatic cholangiocarcinoma: a retrospective analysis of real-world evidence
中文标题:帕博利珠单抗和仑伐替尼联合GEMOX通过不同给药途径(HAIC与静脉内)治疗晚期肝内胆管癌的疗效和安全性:真实世界证据的回顾性分析
汇报人:Hongli Yu
时间:3月28日15:30-16:30
摘要号:OP0072
英文标题:Retrospective Analysis of Efficacy Differences Between Lenvatinib and Sorafenib in Patients with Mid-to-Late Stage Hepatocellular Carcinoma Complicated by Diabetes
中文标题:仑伐替尼与索拉非尼在中晚期肝细胞癌合并糖尿病患者中疗效差异的回顾性分析
汇报人:jiaqi Liu
时间:3月28日15:30-16:30
摘要号:OP0098
英文标题:Effectiveness and Safety of Hepatic Arterial Infusion Chemotherapy for Systemic Chemotherapy Refractory Pancreatic Cancer with Liver Metastases
中文标题:肝动脉灌注化疗对于系统化疗耐药的伴有肝转移的胰腺癌的有效性和安全性
汇报人:Yaqin Wang
时间:3月28日16:30-17:30
摘要号:OP0099
英文标题:Oncolytic virus M1-c6v1 combined with camrelizumab and apatinib in patients with advanced hepatocellular carcinoma: A phase 2 open-label trial evaluating safety, and efficacy
中文标题:溶瘤病毒M1-c6v1联合卡瑞利珠单抗和阿帕替尼治疗晚期肝细胞癌患者:一项评估安全性和有效性的2期开放标签试验
汇报人:Chan Xie
时间:3月28日16:30-17:30
摘要号:OP0101
英文标题:A multicenter case–controlled study on laparoscopic hepatectomy versus microwave ablation as first-line therapy for 3–5 cm hepatocellular carcinoma in patients aged 60 and older
中文标题:腹腔镜肝切除术与微波消融作为60岁及以上患者3-5 cm肝细胞癌一线治疗的多中心病例对照研究
汇报人:Zhen Wang
时间:3月28日16:30-17:30
摘要号:OP0102
英文标题:Efficacy and safety of tremelimumab plus durvalumab in participants from mainland of China with unresectable hepatocellular carcinoma: extension cohort of the randomized, open-label, multicenter, global, Phase 3 HIMALAYA study
中文标题:替西木单抗联合度伐利尤单抗在中国大陆不可切除肝细胞癌参与者中的疗效和安全性:随机、开放标签、多中心、全球、3期HIMALAYA研究的扩展队列
汇报人:秦叔逵
时间:3月28日16:30-17:30
摘要号:OP0161
英文标题:Survival benefit from neoadjuvant transarterial chemoembolization with tyrosine kinase and immune checkpoint inhibitors for resectable intermediate or advanced hepatocellular carcinoma (GUIDANCE002): a multicenter, retrospective study
中文标题:酪氨酸激酶和免疫检查点抑制剂新辅助经动脉化疗栓塞治疗可切除的中晚期肝细胞癌(GUIDANCE002):一项多中心、回顾性研究
汇报人:DaLong Yang
时间:3月29日10:00-11:00
摘要号:OP0176
英文标题:Worldwide burden of liver cancer due to metabolic dysfunction-associated steatohepatitis from 1990 to 2019: insights from the Global Burden of Disease study
中文标题:1990年至2019年代谢功能障碍相关脂肪性肝炎导致的全球肝癌负担:来自全球疾病负担研究的见解
汇报人:Minshan Huang
时间:3月29日10:00-11:00
摘要号:OP0177
英文标题:Burden of pancreatic cancer and its attributable risk factors in 204 countries and territories, 1990-2021: results from the Global Burden of Disease Study 2021
中文标题:1990-2021年,204个国家和地区的胰腺癌负担及其归因风险因素:2021年全球疾病负担研究的结果
汇报人:Kai Jiang
时间:3月29日10:00-11:00
摘要号:OP0189
英文标题:Circulating Tumor-specific Cell-free Tumor DNA is Useful in Monitoring Recurrence of HBV-related HCC after Liver Transplantation
中文标题:循环肿瘤特异性游离肿瘤DNA可用于监测肝移植后HBV相关HCC的复发
汇报人:Shiou-Hwei Yeh
时间:3月29日11:00-12:00
摘要号:OP0218
英文标题:Effectiveness and Safety of Atezolizumab Combined with Lenvatinib as Conversion Therapy for Initially Unresectable Hepatocellular Carcinoma: a Retrospective Study
中文标题:阿替利珠单抗联合仑伐替尼作为初始不可切除肝细胞癌转化治疗的有效性和安全性:一项回顾性研究
汇报人:Ying Luo
时间:3月29日13:30-14:30
摘要号:OP0220
英文标题:AI-Enhanced Tumor Volume Assessment for Hepatocellular Carcinoma Treatment Efficacy: A Superior Alternative to Diameter-Based Evaluation Criteria
中文标题:AI增强肿瘤体积评估肝细胞癌治疗效果:基于直径的评估标准的绝佳替代方案
汇报人:Dianzhe Tian
时间:3月29日13:30-14:30
摘要号:OP0221
英文标题:Alpha-fetoprotein combined with initial tumor shape irregularity in predicting the survival of patients with advanced hepatocellular carcinoma treated with immune-checkpoint inhibitors: a multi-center cohort study
中文标题:甲胎蛋白联合初始肿瘤形状不规则预测免疫检查点抑制剂治疗晚期肝细胞癌患者生存率:一项多中心队列研究
汇报人:Wang Yong Shuai
时间:3月29日13:30-14:30
摘要号:OP0222
英文标题:AKR1B10 as a New Diagnostic and Prognostic Serum Marker for Hepatocellular Carcinoma
中文标题:AKR1B10作为肝细胞癌新的诊断和预后血清标志物
汇报人:曹德良
时间:3月29日13:30-14:30
摘要号:OP0247
英文标题:Circular RNA-based neoantigen vaccine for hepatocellular carcinoma immunotherapy
中文标题:用于肝细胞癌免疫治疗的基于环状RNA的新抗原疫苗
汇报人:Bixing Zhao
时间:3月29日14:30-15:30
摘要号:OP0249
英文标题:4-hydroxyhippuric acid drives SLC22A4+ neutrophils to deteriorate CD8+T cell anti-tumor immunity in hepatocellular carcinoma
中文标题:4-羟基马尿酸驱动SLC22A4+中性粒细胞恶化肝细胞癌CD8+T细胞抗肿瘤免疫
汇报人:Hanyi Zeng
时间:3月29日14:30-15:30
摘要号:OP0250
英文标题:Bridging the Gap Between Imaging and Molecular Characterization: Current Understanding of Radiomics and Radiogenomics in Hepatocellular Carcinoma
中文标题:弥合成像和分子表征之间的差距:目前对肝细胞癌放射组学和放射基因组学的理解
汇报人:Liying Ren
时间:3月29日14:30-15:30
摘要号:OP0251
英文标题:Efficacy and Safety of the Combination of Envafolimab and Lenvatinib in Unresectable Hepatocellular Carcinoma: a Single-arm, Multicentre, Exploratory Phase II Clinical Study
中文标题:恩沃利单抗和仑伐替尼联合治疗不可切除性肝细胞癌的疗效和安全性:一项单臂、多中心、探索性二期临床研究
汇报人:Yunwei Han
时间:3月29日14:30-15:30
摘要号:OP0252
英文标题:A Pilot Study of Adoptive Natural Killer Cell Therapy Combined with Microwave Ablation for Hepatocellular Carcinoma
中文标题:过继性自然杀伤细胞疗法联合微波消融治疗肝细胞癌的初步研究
汇报人:Qian Cai
时间:3月29日14:30-15:30
摘要号:OP0263
英文标题:Effects of Nucleoside analogues on liver fibrosis remission in patients with HBV-related hepatocellular carcinoma
中文标题:核苷类似物对HBV相关肝细胞癌患者肝纤维化缓解的影响
汇报人:JianRong Li
时间:3月29日14:30-15:30
摘要号:OP0269
英文标题:Ethanol decreases CPT2-mediated Carnitine catabolism to promote stemness in alcoholic hepatocellular carcinoma
中文标题:乙醇降低CPT2介导的肉碱分解代谢,促进酒精性肝细胞癌的干性
汇报人:Xiaoxue Yuan
时间:3月29日14:30-15:30
摘要号:OP0281
英文标题:Early Diagnosis of HBV-related HCC: Application of Liquid Biopsy Technology Based on DNA Methylation
中文标题:HBV相关HCC的早期诊断:基于DNA甲基化的液体活检技术的应用
汇报人:Xueying Huang
时间:3月29日15:45-16:45
摘要号:OP0289
英文标题:Baohuoside I inhibits Hepatocellular carcinoma through the UBE2C/P53 Pathway
中文标题:宝活苷I通过UBE2C/P53通路抑制肝细胞癌
汇报人:Xin Zhang
时间:3月29日15:45-16:45
摘要号:OP0293
英文标题:Efficacy and Safety of He-Shu-Xiao-Ji Pill Combined with Standard Treatment Strategy in HBV-related Hepatocellular Carcinoma: A Single-center, Prospective Control, Real-world Cohort Study
中文标题:乙型肝炎病毒相关肝细胞癌患者中,何首乌消积丸联合标准治疗策略的有效性和安全性:一项单中心、前瞻性对照、真实世界队列研究
汇报人:Xiaoning Zhu
时间:3月29日15:45-16:45
摘要号:OP0307
英文标题:Efficacy and safety of SIRT combined with low-dose HAIC, tyrosine kinase inhibitors, and immune checkpoint inhibitors for unresectable large hepatocellular carcinoma
中文标题:SIRT联合低剂量HAIC、酪氨酸激酶抑制剂和免疫检查点抑制剂治疗不可切除的大肝细胞癌的疗效和安全性
汇报人:Mingzhi Hao
时间:3月29日16:45-17:45
摘要号:OP0308
英文标题:Multicohort fecal metagenomes analysis contributes to non-invasive diagnosis for cholangiocarcinoma
中文标题:多队列粪便宏基因组分析有助于胆管癌的非侵入性诊断
汇报人:任志刚
时间:3月29日16:45-17:45
摘要号:OP0309
英文标题:Decade-Long Survival Insights: Upfront Ablation Outperforms Delayed Ablation in Colorectal Liver Oligometastases: A Comprehensive Nationwide Study
中文标题:十年生存洞察:前瞻性消融术在结直肠癌肝寡转移中的效果优于延迟消融术:一项全面的全国性研究
汇报人:Jianming Li
时间:3月29日16:45-17:45
摘要号:OP0327
英文标题:Sorafenib plus transarterial chemoembolization versus sorafenib alone in advanced hepatocellular carcinoma (SELECT): a multicenter, phase 3, randomized, controlled trial
中文标题:索拉非尼联合经动脉化疗栓塞与单用索拉非尼治疗晚期肝细胞癌的比较研究(SELECT):一项多中心、第三阶段、随机、对照试验
汇报人:Yan Zhao
时间:3月29日16:45-17:45
摘要号:OP0332
英文标题:The Efficacy and Safety of Pegylated Interferon Alpha Treatment in Patients with HBV Related Cirrhosis and HCC after Radical Surgery: Preliminary Data From The TERMINATOR Project
中文标题:聚乙二醇干扰素α治疗在HBV相关肝硬化和HCC患者中的疗效和安全性:来自TERMINATOR项目的初步数据
汇报人:窦晓光
时间:3月29日16:45-17:45
摘要号:OP0337
英文标题:Gut-liver axis modulation empowers natural killer T cells for liver cancer immunotherapy
中文标题:肠道-肝脏轴调节赋予自然杀伤T细胞用于肝癌免疫治疗的能力
汇报人:Ting Luo
时间:3月30日08:00-09:00
摘要号:OP0341
英文标题:Predictive Value of pgRNA for Recurrence in Advanced Hepatocellular Carcinoma and Its Potential Mechanisms
中文标题:预测性价值的pgRNA对于晚期肝细胞癌复发及其潜在机制
汇报人:Yifan Han
时间:3月30日09:00-10:00
摘要号:OP0343
英文标题:PHGDH acts as an RNA-binding protein to stabilize PRKCD mRNA and promote hepatocellular carcinoma progression
中文标题:PHGDH作为一种RNA结合蛋白,能够稳定PRKCD mRNA并促进肝细胞癌的进展
汇报人:bin cheng
时间:3月30日09:00-10:00
摘要号:OP0345
英文标题:Long Noncoding RNA FTX Exhibits Dual Roles in Hepatocellular Carcinoma Progression: Implications for Anoikis Resistance and Metastasis
中文标题:长非编码RNA FTX在肝细胞癌进展中表现出双重作用:对抵抗失巢凋亡和转移的启示
汇报人:Tao Li
时间:3月30日09:00-10:00
摘要号:OP0384
英文标题:Detection of MVI in HCC using spatiotemporal radiomics of contrast-enhanced ultrasound: a deep learning model with transcriptomics correlation
中文标题:使用对比增强超声的时空放射组学检测肝细胞癌中的微血管侵犯:一个具有转录组学相关性的深度学习模型
汇报人:Chuan Pang
时间:3月30日10:00-11:00
摘要号:OP0385
英文标题:Assessment of the Diagnostic Efficacy of a Novel Liver Cancer Biomarker: Multigene Methylation
中文标题:评估一种新型肝癌生物标志物的诊断效能:多基因甲基化
汇报人:Xiangsha Kong
时间:3月30日10:00-11:00
摘要号:OP0389
英文标题:A Novel Mitochondrial Micropeptide HRMM1 Interacts with ATP5B to Promote Energy Metabolism and Hepatocellular Carcinoma Progression
中文标题:一种新型线粒体微肽HRMM1与ATP5B相互作用以促进能量代谢和肝细胞癌进展
汇报人:Wenli Xu
时间:3月30日10:00-11:00
摘要号:OP0392
英文标题:The role and pathogenesis of hydrogen sulfide in angiogenesis of HCC vascularized organoid
中文标题:硫化氢在肝细胞癌血管化器官样体血管生成中的作用和发病机制
汇报人:Lingna Lyu
时间:3月30日10:00-11:00
摘要号:PL0014
英文标题:SCG101 TCR-T Therapy Achieves Rapid and Sustained HBsAg Reduction with >30% HBsAg Loss in HBV-Related Hepatocellular Carcinoma Patients
中文标题:SCG101 TCR-T疗法在HBV相关肝细胞癌患者中实现快速且持续的HBsAg降低,超过30%的患者HBsAg减少
汇报人:Shunda Du
时间:3月29日13:30-15:00
摘要号:YI0009
英文标题:Hepatic TM6SF2 activates anti-tumor immunity to suppressed metabolic dysfunction-associated steatotic liver disease–associated hepatocellular carcinoma and boosts immunotherapy
中文标题:肝脏TM6SF2激活抗肿瘤免疫以抑制代谢功能障碍相关脂肪肝病相关肝细胞癌,并增强免疫治疗
汇报人:Yating ZHANG
时间:3月29日11:00-12:00
摘要号:YI0016
英文标题:Prognostic Discordance Among Five Major Staging Systems for Early-stage Hepatocellular Carcinoma: A Multi-institutional Analysis of 4,623 Patients
中文标题:早期肝细胞癌五大分期系统预后不一致:一项涉及4623名患者的多机构分析
汇报人:Tian Yang
时间:3月29日11:00-12:00
摘要号:YI0024
英文标题:Microwave Ablation versus Repeat Liver Resection for Recurrent Intrahepatic Cholangiocarcinoma within Milan Criteria: A Long-term Multicenter Cohort Study
中文标题:微波消融与重复肝切除术治疗米兰标准内复发性肝内胆管癌的长期多中心队列研究
汇报人:Chuan Pang
时间:3月30日08:00-09:00
摘要号:YI0025
英文标题:Outcomes of Conversion Surgery After Immune Checkpoint Inhibitor-Based Combination Therapy in Initially Unresectable Hepatocellular Carcinoma: A Retrospective Cohort Study
中文标题:基于免疫检查点抑制剂联合治疗后转换手术在最初不可切除的肝细胞癌中的结果:一项回顾性队列研究
汇报人:Mingjian Piao
时间:3月30日08:00-09:00
排版编辑:肿瘤资讯-Skye