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2024 ESMO|肺癌相关专场LBA信息速览!

08月21日
整理:肿瘤资讯
来源:2024 ESMO 官网

2024欧洲肿瘤学会(ESMO 2024)年会即将来袭,此次会议将于欧洲中部夏令时间(CET)9月13日-17日在西班牙巴塞罗那举行。
近日,ESMO官方已公布所有口头摘要题目及作者信息。【肿瘤资讯】特别整理本次公布的肺癌相关专场Late-breaking abstracts(LBA)的重磅研究标题,以飨读者。

Proffered paper session: NSCLC metastatic


专场时间:2024年9月14日,08:30-10:00
专场地点:Barcelona Auditorium - Hall 2


摘要号:LBA52

Interim Analysis of GALAXIES Lung-201: Phase 2, Randomized, Open-label Platform Study of Belrestotug Plus Dostarlimab in Patients (pts) With Previously Untreated Locally Advanced/Metastatic (LA/M) PD-L1 High (TPS >/=50%) Non-Small Cell Lung Cancer (NSCLC)

GALAXIES Lung-201的中期分析:Belrestotug联合Dostarlimab治疗既往未经治疗的局部晚期/转移性(LA/M)PD-L1高水平(TPS >/=50%)非小细胞肺癌(NSCLC)患者的II期、随机化、开放标签平台研究

讲者:David R Spigel (Nashville, United States of America, TN)


摘要号:LBA53

Nivolumab (NIVO) plus relatlimab with platinum-doublet chemotherapy (PDCT) vs NIVO + PDCT as first-line (1L) treatment (tx) for stage IV or recurrent NSCLC: results from the randomized phase 2 RELATIVITY-104 study

纳武利尤单抗(NIVO)+relatlimab联合铂类双联化疗(PDCT)与NIVO+PDCT作为IV期或复发性NSCLC的一线(1 L)治疗(tx):来自随机化II期RELATIVITY-104研究的结果

讲者:Nicolas Girard (Paris, France)


摘要号:LBA54

Amivantamab Plus Chemotherapy vs Chemotherapy in EGFR-mutated, Advanced Non-small Cell Lung Cancer After Disease Progression on Osimertinib: 2nd Interim Overall Survival From MARIPOSA-2

埃万妥单抗加化疗与化疗在EGFR突变的晚期非小细胞肺癌患者中的比较:接受奥希替尼治疗后疾病进展:MARIPOSA-2的第2个中期总生存期

讲者:Sanjay Popat (London, United Kingdom) 



摘要号:LBA55

Mechanisms of Acquired Resistance to First-line Amivantamab Plus Lazertinib Versus Osimertinib in Patients With EGFR-mutant Advanced Non-Small Cell Lung Cancer: An Early Analysis from the Phase 3 MARIPOSA Study

EGFR突变型晚期非小细胞肺癌患者对一线埃万妥单抗 + Lazertinib与奥希替尼的获得性耐药机制:来自III期MARIPOSA研究的早期分析

讲者:Benjamin Besse (Villejuif, Cedex, France, CEDEX)


Proffered paper session: Non-metastatic NSCLC


专场时间:2024年9月13日,14:00-15:30
专场地点:Bilbao Auditorium - Hall 2


摘要号:LBA48

CCTG BR.31: A global, double-blind placebo-controlled, randomized phase III study of adjuvant durvalumab in completely resected non-small-cell lung cancer (NSCLC)

CCTG BR.31: 一项全球性的、双盲安慰剂对照的、随机的Ⅲ期研究,针对完全切除的非小细胞肺癌(NSCLC)进行了度伐利尤单抗辅助治疗

讲者:Glenwood Goss (Ottawa, Canada, Ontario)


摘要号:LBA81

Durvalumab (D) as consolidation therapy in limited-stage SCLC (LS-SCLC): outcomes by prior concurrent chemoradiotherapy (cCRT) regimen and prophylactic cranial irradiation (PCI) use in the ADRIATIC trial


度伐利尤单抗(D)作为局限期小细胞肺癌(LS-SCLC)巩固治疗:ADRIATIC试验中既往同步放化疗放疗(cCRT)方案和预防性颅内放疗(PCI)使用情况的结果

讲者:Suresh Senan (Amsterdam, Netherlands)


摘要号:LBA83

PECATI: A phase 2 trial to evaluate the efficacy and safety of lenvatinib in combination with pembrolizuma pretreated advanced B3-thymoma and thymic carcinoma

PECATI: 一项评价仑伐替尼联合帕博利珠单抗治疗晚期B3-胸腺瘤和胸腺癌的疗效和安全性的II期试验

讲者:Jordi Remon Masip (Villejuif, Cedex, France)


Mini oral session 1: Non-metastatic NSCLC


专场时间:2024年9月15日,10:15-11:30
专场地点:Barcelona Auditorium - Hall 2


摘要号:LBA49

Associations of ctDNA clearance (CL) during neoadjuvant Tx with pathological response and event-free survival (EFS) in pts with resectable NSCLC (R-NSCLC): expanded analyses from AEGEAN

可切除NSCLC(R-NSCLC)患者新辅助治疗期间ctDNA清除率(CL)与病理学缓解和无事件生存期(EFS)的相关性:来自AEGEAN的扩展分析

讲者:Martin Reck (Grosshansdorf, Germany)


摘要号:LBA50

Perioperative nivolumab (NIVO) v placebo (PBO) in patients (pts) with resectable NSCLC: clinical update from the phase 3 CheckMate 77T study

可切除NSCLC患者(患者)围手术期纳武利尤单抗(NIVO)与安慰剂(PBO)的比较:来自3期CheckMate 77T研究的临床更新

讲者:Mariano Provencio Pulla (Majadahonda, Spain, Madrid)


摘要号:LBA51

Circulating tumor DNA (ctDNA) dynamics and treatment responses in chemotherapy-ineligible patients (pts) with unresectable Stage III NSCLC from the phase 2 DUART trial

2期DUART试验中不适合化疗的不可切除III期NSCLC患者的循环肿瘤DNA(ctDNA)动力学和治疗应答

讲者:Andrea Riccardo Filippi (Milan, Italy)


Mini oral session: NSCLC metastatic


专场时间:2024年9月14日,10:15-11:45
专场地点:Santander Auditorium - Hall 5


摘要号:LBA56

Updated Efficacy and Safety From the Phase 2 PHAROS Study of Encorafenib Plus Binimetinib in Patients With BRAF V600E-Mutant Metastatic NSCLC (mNSCLC)

在BRAF V600E突变型转移性NSCLC(mNSCLC)患者中开展的II期PHAROS研究中更新的Encorafenib + Binimetinib的疗效和安全性

讲者:Gregory J. Riely (New York, United States of America, NY)


摘要号:LBA57

Adagrasib (ADA) vs docetaxel (DOCE) in patients (pts) with KRASG12C-mutated advanced NSCLC and baseline brain metastases (BM): results from KRYSTAL-12

Adagrasib(ADA)与多西他赛(DOCE)在KRASG12C突变晚期NSCLC伴基底脑转移(BM)患者中的比较:KRYSTAL-12的结果

讲者:Fabrice Barlesi (Villejuif, France, CEDEX 20)



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