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【2024 ASCO】先睹为快:儿童肿瘤领域最新重大研究进展概览

04月30日
编译:肿瘤资讯
来源:肿瘤资讯

2024美国临床肿瘤学会(ASCO 2024)年会即将于2024年5月31日-6月4日在美国芝加哥举行。【肿瘤资讯】特别整理儿童肿瘤重磅研究进展!

口头摘要专场(Oral Abstract Session)

摘要号:10000

Efficacy and safety of entrectinib in children with extracranial solid or primary central nervous system (CNS) tumors harboring NTRK or ROS1 fusions

恩曲替尼在携带NTRK或ROS1融合基因的儿童非中枢神经系统(CNS)实体瘤或原发性中枢神经系统肿瘤中的疗效与安全性

讲者:Ami Desai, University of Chicago Medical Center

摘要号:10001

Phase IB study of tovorafenib for children with relapsed/recurrent low-grade gliomas and other MAPK pathway activated tumors

tovorafenib用于治疗复发/难治性低级别胶质瘤及其他MAPK通路激活肿瘤儿童的IB期研究

讲者:Karen Wright, Dana-Farber/Boston Children’s Cancer and Blood Disorders Center

摘要号:10002

Efficacy and safety of erdafitinib in pediatric patients with advanced solid tumors and FGFR alterations in the phase 2 RAGNAR trial

在RAGNAR试验的第2阶段中,厄达替尼在携带FGFR变异的儿童晚期实体瘤患者中的疗效和安全性

讲者:Olaf Witt, Hopp Children’s Cancer Center Heidelberg (KiTZ), Heidelberg University Hospital and German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT)

摘要号:10003

Impact of an objective scoring system on initiation of therapy in patients with International Neuroblastoma Risk Group Staging System (INRGSS) stage MS neuroblastoma: A report from the Children’s Oncology Group

客观评分系统对使用国际神经母细胞瘤风险组分期系统(INRGSS)MS期神经母细胞瘤患者开始治疗的影响:来自儿童肿瘤学组的报告

讲者:Leonora Slatnick, University of Utah

摘要号:10004

A pilot study of post-consolidation chemoimmunotherapy for high-risk neuroblastoma (ANBL19P1): A report from the Children’s Oncology Group

针对高危神经母细胞瘤(ANBL19P1)的巩固后化疗免疫治疗的初步研究:来自儿童肿瘤学组的报告

讲者:Ami Desai, University of Chicago Medical Center

摘要号:10009

Uptake of germline cancer genetic services in a randomized trial of remote telehealth services as compared to usual care: A report from the Childhood Cancer Survivor Study (CCSS)

在远程远程医疗服务与常规护理相比的随机试验中,儿童癌症幸存者研究(CCSS)的报告:对生殖系癌症遗传服务的接受情况

讲者:Tara Henderson, University of Chicago Pritzker School of Medicine

摘要号:10010

A stepped wedge trial of a healthcare provider–focused intervention to increase human papillomavirus (HPV) vaccine initiation among survivors of childhood cancer

一项阶梯楔形试验:通过针对医疗提供者的干预措施,提高儿童癌症幸存者中人类乳头瘤病毒(HPV)疫苗的接种

讲者:Wendy Landier, Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham

摘要号:10011

Communicating cardiovascular health information and improving coordination with primary care: A Childhood Cancer Survivor Study randomized trial

传递心血管健康信息并与初级保健改善协调:一项儿童癌症幸存者研究的随机试验

讲者:Eric Chow, Fred Hutchinson Cancer Center

摘要号:10012

Access for adolescents and young adults with hard-to-cure cancer to PROFYLE: The pan-Canadian precision oncology pipeline

为患有难以治愈癌症的青少年和年轻成人提供PROFYLE的接入:加拿大全国精准肿瘤学通道

讲者:Lesleigh Abbott, The Children's Hospital of Eastern Ontario

摘要号:10015

Vincristine (VCR) pharmacokinetics (PK) in infants dosed using a body surface area (BSA) banded dosing table and in older children dosed based on BSA: A pediatric early phase clinical trial network study (PEPN22P1)

使用体表面积(BSA)分段剂量表给药的婴儿和基于BSA给药的较大儿童的长春新碱(VCR)药代动力学(PK):儿童早期阶段临床试验网络研究(PEPN22P1)

讲者:Emily Blauel-Bocko, Children's Hospital Colorado

摘要号:10016

Evolution of tisagenlecleucel use for the treatment of pediatric and young adult relapsed/refractory (r/r) B-cell acute lymphoblastic leukemia (B-ALL): Center for International Blood & Marrow Transplant Research (CIBMTR) registry results

 斯利弗名用于治疗儿童和年轻成人复发/难治性(r/r)B细胞急性淋巴细胞性白血病(B-ALL)的进展:国际血液与骨髓移植研究中心(CIBMTR)注册结果

讲者:Rayne Rouce, Department of Pediatrics, Baylor College of Medicine

口头摘要速递专场(Rapid Oral Abstract Session)

摘要号:10021

Impact of breaks in therapy on survival for pediatric patients with relapsed or refractory solid tumors: A single-center study

治疗中断对患有复发或难治性实体瘤的儿童患者生存率的影响:一项单中心研究

讲者:Matthew McEvoy, Texas Children's Cancer and Hematology Centers and Division of Palliative Care

摘要号:10022

Safety and efficacy of selpercatinib in pediatric patients with RET-altered solid tumors: Updated results from LIBRETTO-121

在携带RET变异的儿童实体瘤患者中,塞普替尼的安全性和有效性:LIBRETTO-121研究的更新结果

讲者:Daniel Morgenstern, The Hospital for Sick Children, University of Toronto

摘要号:10024

Comparing the impact of insufficient physical activity on cardiovascular disease in survivors of childhood Hodgkin lymphoma and sibling controls: A report from the Childhood Cancer Survivor Study (CCSS)

比较儿童霍奇金淋巴瘤幸存者与兄弟姐妹对照组中体力活动不足对心血管疾病影响的研究:儿童癌症幸存者研究(CCSS)的报告

讲者:Aron Onerup, St. Jude Children's Research Hospital

摘要号:10025

Tamoxifen for breast cancer prevention among survivors of pediatric lymphoma previously treated with chest radiation: Clinical benefits, harms and tradeoffs

他莫昔芬用于接受胸部放疗的儿童淋巴瘤幸存者乳腺癌预防:临床益处、风险和权衡

讲者:Jennifer Yeh, Boston Children's Hospital and Harvard Medical School

摘要号:10026

Treatment modifications and mortality among female patients with subsequent breast cancer: A report from the Childhood Cancer Survivor Study (CCSS)

女性随后患乳腺癌患者的治疗调整与死亡率:儿童癌症幸存者研究(CCSS)的报告

讲者:Lucie Turcotte, University of Minnesota Medical School


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